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Improved quantification of the cyanobacteria metabolite, β-methylamino-l-alanine (BMAA) using HPLC-MS/MS detection of its dansyl chloride derivative referenced to a15N-labeled internal standard

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Historic disagreement regarding the prevalence and abundance of BMAA may be due in part to false-negative results arising from deuterated internal standards and the derivatization conditions used in prior studies. Click to show full abstract

Historic disagreement regarding the prevalence and abundance of BMAA may be due in part to false-negative results arising from deuterated internal standards and the derivatization conditions used in prior studies.

Keywords: methylamino alanine; quantification cyanobacteria; improved quantification; metabolite methylamino; bmaa; cyanobacteria metabolite

Journal Title: Analytical Methods
Year Published: 2019

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