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Synthesis of N-unsubstituted cycloalkylimines containing a 4 to 8-membered ring.

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Primary cycloalkylimines with a 4 to 8-membered ring were synthesized by dehydrocyanation of the corresponding α-aminonitriles on solid potassium hydroxide via a vacuum gas-solid reaction. Imine-enamine tautomerism has been demonstrated… Click to show full abstract

Primary cycloalkylimines with a 4 to 8-membered ring were synthesized by dehydrocyanation of the corresponding α-aminonitriles on solid potassium hydroxide via a vacuum gas-solid reaction. Imine-enamine tautomerism has been demonstrated at room temperature for the most kinetically stable derivatives.

Keywords: containing membered; membered ring; cycloalkylimines containing; unsubstituted cycloalkylimines; synthesis unsubstituted

Journal Title: Chemical communications
Year Published: 2019

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