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Robust scalable synthesis of a bis-urea derivative forming thixotropic and cytocompatible supramolecular hydrogels.

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Synthetic hydrogels address a need for affordable, industrially scalable scaffolds for tissue engineering. Herein, a novel low molecular weight gelator is reported that forms self-healing supramolecular hydrogels. Its robust synthesis… Click to show full abstract

Synthetic hydrogels address a need for affordable, industrially scalable scaffolds for tissue engineering. Herein, a novel low molecular weight gelator is reported that forms self-healing supramolecular hydrogels. Its robust synthesis can be performed in a solvent-free manner using ball milling. Strikingly, encapsulated cells spread and proliferate without specific cell adhesion ligands in the nanofibrous material.

Keywords: supramolecular hydrogels; robust scalable; hydrogels robust; synthesis bis; scalable synthesis; synthesis

Journal Title: Chemical communications
Year Published: 2019

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