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Access to 2-naphthols via Ru(ii)-catalyzed C-H annulation of nitrones with α-diazo sulfonyl ketones.

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Efficient synthesis of 2-naphthols was realized by Ru(ii)-catalyzed C-H activation of aryl nitrones and intermolecular [3+3] annulation with α-diazo sulfonyl ketones under redox-neutral conditions. Easily available α-diazo sulfonyl ketones act… Click to show full abstract

Efficient synthesis of 2-naphthols was realized by Ru(ii)-catalyzed C-H activation of aryl nitrones and intermolecular [3+3] annulation with α-diazo sulfonyl ketones under redox-neutral conditions. Easily available α-diazo sulfonyl ketones act as a three-carbon component in the reaction.

Keywords: annulation; via catalyzed; access naphthols; diazo sulfonyl; sulfonyl ketones; naphthols via

Journal Title: Chemical communications
Year Published: 2019

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