Cascade cyclization reactions of S3˙- in situ generated from S2- with 1,3-enynes for the chemoselective synthesis of 2,3,5-trisubstituted thiophenes and 3-thienyl disulfides controlled by sulfide salts are developed. These two… Click to show full abstract
Cascade cyclization reactions of S3˙- in situ generated from S2- with 1,3-enynes for the chemoselective synthesis of 2,3,5-trisubstituted thiophenes and 3-thienyl disulfides controlled by sulfide salts are developed. These two protocols provide new, environment-friendly and simple strategies to construct 2,3,5-trisubstituted thiophenes and 3-thienyl disulfides via the formation of two and six C-S bonds, respectively.
Keywords:
thiophenes thienyl;
thienyl disulfides;
synthesis trisubstituted;
trisubstituted thiophenes;
chemoselective synthesis
Journal Title: Chemical communications
Year Published: 2019
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Journal Title: Chemical communications
Year Published: 2019
Link to full text (if available)
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recommendations!