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A nanoparticle enabled focused ultrasound-stimulated magnetic resonance imaging spotlight.

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Periodic high-intensity focused ultrasound modulation of a nanoparticle generates reversible MRI T1 relaxivity changes at the 1.5 mm3 focal point causing periodic T1-weighted signal changes. Fourier analysis extracts signal changes… Click to show full abstract

Periodic high-intensity focused ultrasound modulation of a nanoparticle generates reversible MRI T1 relaxivity changes at the 1.5 mm3 focal point causing periodic T1-weighted signal changes. Fourier analysis extracts signal changes at the modulation frequency, and a modulation enhancement map spotlights the precise region of interest by increasing contrast almost 100-fold.

Keywords: focused ultrasound; ultrasound stimulated; nanoparticle; stimulated magnetic; nanoparticle enabled; enabled focused

Journal Title: Chemical communications
Year Published: 2019

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