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A fluorogenic probe for tracking GSH flux in developing neurons.

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Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in… Click to show full abstract

Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a fluorogenic probe capable of imaging subtle GSH fluctuations in developing neurons.

Keywords: flux developing; gsh flux; probe; developing neurons; fluorogenic probe; probe tracking

Journal Title: Chemical communications
Year Published: 2019

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