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Step-wise functionalization of polysiloxane towards a versatile dual-response fluorescent probe and elastomer for the detection of H2S in two-photon and NO in near-infrared modes.

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Simultaneous detection of gasotransmitters such as NO and H2S is a crucial task to investigate the complicated relationship between NO and H2S. In this work, we presented a new approach… Click to show full abstract

Simultaneous detection of gasotransmitters such as NO and H2S is a crucial task to investigate the complicated relationship between NO and H2S. In this work, we presented a new approach to construct a dual response fluorescent probe for NO/H2S by step-wise functionalization of polysiloxanes. A near-infrared (NIR) and two-photon (TP) fluorescent probe, P-CYN, was fabricated for respectively visualizing H2S and NO in vivo. This work presented a powerful tool for the investigation of the relationship between gasotransmitters, and provided a valid strategy for further design of dual-response fluorescent probes.

Keywords: fluorescent probe; fluorescent; dual response; response fluorescent; h2s

Journal Title: Chemical communications
Year Published: 2020

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