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Synthesis of spiro[2,3-dihydrofuran-3,3′-oxindole] derivatives via a multi-component cascade reaction of α-diazo esters, water, isatins and malononitrile/ethyl cyanoacetate

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We report a green synthesis of spiro[2,3-dihydrofuran-3,3′-oxindole] derivatives which are of potential value in medicinal chemistry. Click to show full abstract

We report a green synthesis of spiro[2,3-dihydrofuran-3,3′-oxindole] derivatives which are of potential value in medicinal chemistry.

Keywords: oxindole derivatives; spiro dihydrofuran; synthesis spiro; dihydrofuran oxindole; chemistry

Journal Title: Green Chemistry
Year Published: 2019

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