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Synthesis, screening and biological activity of potent thiosemicarbazone compounds as a tyrosinase inhibitor

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Inhibitors are designed based on coordination chemistry and catalytic circle of the tyrosinase, coordination atoms binds to copper and blocks enzyme activity, indicated that thiosemicarbazone species possess good potential as… Click to show full abstract

Inhibitors are designed based on coordination chemistry and catalytic circle of the tyrosinase, coordination atoms binds to copper and blocks enzyme activity, indicated that thiosemicarbazone species possess good potential as tyrosinase inhibitors.

Keywords: thiosemicarbazone; biological activity; activity; screening biological; synthesis screening; chemistry

Journal Title: New Journal of Chemistry
Year Published: 2019

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