"Reactive oxygen species-responsive theranostic nanoparticles for enhanced hypoxic tumor photodynamic therapyviasynchronous HIF-1α inhibition and ATP depletion"

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Reactive oxygen species-responsive theranostic nanoparticles for enhanced hypoxic tumor photodynamic therapyviasynchronous HIF-1α inhibition and ATP depletion

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ROS-responsive nanoparticles were designed to co-deliver the small molecule HIF-1α inhibitor Doxy and the photosensitizer IR780 for enhanced PDT efficiency. Click to show full abstract

ROS-responsive nanoparticles were designed to co-deliver the small molecule HIF-1α inhibitor Doxy and the photosensitizer IR780 for enhanced PDT efficiency.

Keywords: hif; species responsive; theranostic nanoparticles; reactive oxygen; oxygen species; responsive theranostic

Journal Title: Materials Chemistry Frontiers
Year Published: 2019

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