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Why electrostatically enhanced thiourea is better than Schreiner's thiourea in both catalytic activity and regioselectivity?

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Electrostatically enhanced thiourea is more active and efficient than Schreiner's thiourea in the ring-opening aminolysis of styrene oxide with aniline, and the underlying reasons were explored by DFT calculations. Click to show full abstract

Electrostatically enhanced thiourea is more active and efficient than Schreiner's thiourea in the ring-opening aminolysis of styrene oxide with aniline, and the underlying reasons were explored by DFT calculations.

Keywords: better schreiner; schreiner thiourea; electrostatically enhanced; thiourea better; enhanced thiourea

Journal Title: Organic Chemistry Frontiers
Year Published: 2019

Link to full text (if available)


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