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The rigidification of the high-energy conformation of shikimic acid was used to enhance inhibitor efficacy against shikimate kinase enzyme, an attractive target for antibiotic drug discovery. Click to show full abstract
The rigidification of the high-energy conformation of shikimic acid was used to enhance inhibitor efficacy against shikimate kinase enzyme, an attractive target for antibiotic drug discovery.
Keywords:
shikimic acid;
inhibitor efficacy;
kinase enzyme;
efficacy shikimate;
shikimate kinase
Journal Title: Organic Chemistry Frontiers
Year Published: 2019
Link to full text (if available)
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Journal Title: Organic Chemistry Frontiers
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!