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Rhodium-catalyzed biheteroaryl-2-carbonitrile synthesis via double C–H activation

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Rhodium(iii)-catalyzed double C–H activation and in situ dealcoholization to generate biheteroaryl-2-carbonitriles have been developed via a CDC mechanism, in which benzimidates act as both directing groups and the precursors of… Click to show full abstract

Rhodium(iii)-catalyzed double C–H activation and in situ dealcoholization to generate biheteroaryl-2-carbonitriles have been developed via a CDC mechanism, in which benzimidates act as both directing groups and the precursors of nitrile groups.

Keywords: rhodium catalyzed; catalyzed biheteroaryl; double activation; activation; biheteroaryl carbonitrile

Journal Title: Organic Chemistry Frontiers
Year Published: 2019

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