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Asymmetric organocatalyzed reaction sequence of 2-hydroxy cinnamaldehydes and acyclic N-sulfonyl ketimines to construct diverse chiral bridged polycyclic aminals

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2-Hydroxy cinnamaldehydes and acyclic N-sulfonyl ketimines were used as multisite substrates in an iminium catalysis triggered sequential process, leading to diverse chiral bridged polycyclic aminals in a highly regio- and… Click to show full abstract

2-Hydroxy cinnamaldehydes and acyclic N-sulfonyl ketimines were used as multisite substrates in an iminium catalysis triggered sequential process, leading to diverse chiral bridged polycyclic aminals in a highly regio- and stereoselective manner.

Keywords: cinnamaldehydes acyclic; diverse chiral; chiral bridged; acyclic sulfonyl; hydroxy cinnamaldehydes; sulfonyl ketimines

Journal Title: Organic Chemistry Frontiers
Year Published: 2019

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