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A simple organocatalytic system provides efficient access to a series of densely substituted chiral succinimides bearing a quaternary–tertiary carbon stereocenter sequence in good yields, with high diastereo- and enantioselectivities through… Click to show full abstract
A simple organocatalytic system provides efficient access to a series of densely substituted chiral succinimides bearing a quaternary–tertiary carbon stereocenter sequence in good yields, with high diastereo- and enantioselectivities through enantioselective conjugate addition of unreactive α-alkyl cyclic ketones to maleimides under microwave-assisted conditions.
Keywords:
alkyl cyclic;
ketones maleimides;
substituted chiral;
densely substituted;
cyclic ketones;
chiral succinimides
Journal Title: Organic chemistry frontiers
Year Published: 2020
Link to full text (if available)
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Journal Title: Organic chemistry frontiers
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!