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Direct synthesis of 2-oxo-acetamidines from methyl ketones, aromatic amines and DMF via copper-catalyzed C(sp3)–H amidination

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A convenient method for the synthesis of 2-oxo-acetamidines from methyl ketones using aromatic amines and DMF as nitrogen sources is reported via copper-catalyzed C(sp3)–H amidination. Click to show full abstract

A convenient method for the synthesis of 2-oxo-acetamidines from methyl ketones using aromatic amines and DMF as nitrogen sources is reported via copper-catalyzed C(sp3)–H amidination.

Keywords: acetamidines methyl; synthesis oxo; amines dmf; aromatic amines; oxo acetamidines; methyl ketones

Journal Title: RSC Advances
Year Published: 2019

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