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Synthesis of tetracyclic indolin-3-ones through Pd-catalyzed intramolecular deacetylative dearomatization of 3-acetoxy-indoles

An efficient palladium-catalyzed intramolecular deacetylative dearomatization reaction of 3-acetoxyindoles is disclosed, affording tetracyclic indolin-3-ones bearing C2-quaternary stereocenters in good yields. Click to show full abstract

An efficient palladium-catalyzed intramolecular deacetylative dearomatization reaction of 3-acetoxyindoles is disclosed, affording tetracyclic indolin-3-ones bearing C2-quaternary stereocenters in good yields.

Keywords: intramolecular deacetylative; tetracyclic indolin; indolin ones; catalyzed intramolecular; deacetylative dearomatization

Journal Title: RSC Advances
Year Published: 2019

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