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A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring

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A new family of anticancer compounds has been derived from oxaliplatin by inserting a double-bond between carbons 4 and 5 of the 1,2-diaminocyclohexane ring. Click to show full abstract

A new family of anticancer compounds has been derived from oxaliplatin by inserting a double-bond between carbons 4 and 5 of the 1,2-diaminocyclohexane ring.

Keywords: minimal structural; tumour resistance; overcome tumour; variation overcome; resistance oxaliplatin; structural variation

Journal Title: RSC Advances
Year Published: 2019

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