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Single-cell identification by microfluidic-based in situ extracting and online mass spectrometric analysis of phospholipids expression†

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This work describes a microfluidic system for in situ extraction of a single-cell and its phosphatidylcholine analysis through mass spectrometry. This approach uncovered cellular heterogeneity among seemingly identical cells and… Click to show full abstract

This work describes a microfluidic system for in situ extraction of a single-cell and its phosphatidylcholine analysis through mass spectrometry. This approach uncovered cellular heterogeneity among seemingly identical cells and provided a new platform for identification and classification of cells.

Keywords: single cell; analysis; mass; cell identification; cell

Journal Title: Chemical Science
Year Published: 2019

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