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We have developed a novel near-infrared ratiometric fluorescent theranostic nanoprobe. Upon reaction with glutathione, it releases a near-infrared fluorophore and chemotherapy drug. Notably, this nanoprobe can selectively kill HeLa and… Click to show full abstract
We have developed a novel near-infrared ratiometric fluorescent theranostic nanoprobe. Upon reaction with glutathione, it releases a near-infrared fluorophore and chemotherapy drug. Notably, this nanoprobe can selectively kill HeLa and HepG-2 cancer cells over normal HUVEC cells with negligible side effects. Furthermore, this nanoprobe has been successfully applied to real-time fluorescence tracking and imaging cancer therapy in mice.
Keywords:
ratiometric self;
infrared ratiometric;
near infrared;
cancer;
theranostic nanoprobe
Journal Title: Chemical communications
Year Published: 2020
Link to full text (if available)
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Journal Title: Chemical communications
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!