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Cell organelle targeting of near-infrared croconaine dye controls photothermal outcome.

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Near-infrared croconaine-peptide conjugates that target the cell nucleus promote photothermal induced cell death. In contrast, a croconaine-morpholine conjugate that targets the cell lysosomes promotes lysosome permeabilization without measurable cell phototoxicity. Click to show full abstract

Near-infrared croconaine-peptide conjugates that target the cell nucleus promote photothermal induced cell death. In contrast, a croconaine-morpholine conjugate that targets the cell lysosomes promotes lysosome permeabilization without measurable cell phototoxicity.

Keywords: infrared croconaine; near infrared; organelle targeting; cell organelle; croconaine; cell

Journal Title: Chemical communications
Year Published: 2020

Link to full text (if available)


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