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Microcavity array supported lipid bilayer models of ganglioside - influenza hemagglutinin1 binding.

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The binding of influenza receptor (HA1) to membranes containing different glycosphingolipid receptors was investigated at Microcavity Supported Lipid Bilayers (MSLBs). We observed that HA1 preferentially binds to GD1a but the… Click to show full abstract

The binding of influenza receptor (HA1) to membranes containing different glycosphingolipid receptors was investigated at Microcavity Supported Lipid Bilayers (MSLBs). We observed that HA1 preferentially binds to GD1a but the diffusion coefficient of the associated complex at lipid bilayer is approximately double that of the complexes formed by HA1 GM1 or GM3.

Keywords: lipid bilayer; microcavity array; supported lipid; array supported

Journal Title: Chemical communications
Year Published: 2020

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