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Boosting the sensitivity of in vitroβ-lactam allergy diagnostic tests.

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The synthesis of structurally new haptens and the development of suitable antigens are essential for boosting the sensitivity of drug allergy diagnostic testing. Unprecedented structural antigens for benzylpenicillin and amoxicillin… Click to show full abstract

The synthesis of structurally new haptens and the development of suitable antigens are essential for boosting the sensitivity of drug allergy diagnostic testing. Unprecedented structural antigens for benzylpenicillin and amoxicillin are characterised and evaluated in a cohort of 70 subjects with a turnkey solution based on consumer electronics.

Keywords: boosting sensitivity; sensitivity vitro; diagnostic tests; allergy diagnostic; vitro lactam; lactam allergy

Journal Title: Chemical communications
Year Published: 2020

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