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Hydrophobicity-driven folding and seeded polymerization of cystine-based dimeric diamides in aqueous media.

Seeded supramolecular polymerization of cystine-based dimeric diamides with aromatic substituents at the C- and N-termini was achieved in aqueous media. Theoretical and spectroscopic studies reveal that the terminal groups play… Click to show full abstract

Seeded supramolecular polymerization of cystine-based dimeric diamides with aromatic substituents at the C- and N-termini was achieved in aqueous media. Theoretical and spectroscopic studies reveal that the terminal groups play crucial roles in slowing spontaneous assembly through formation of a folded conformation and guiding molecular alignment in the aggregated state.

Keywords: cystine based; aqueous media; based dimeric; dimeric diamides; polymerization cystine

Journal Title: Chemical communications
Year Published: 2020

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