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Developing benign syntheses using ion pairs via solvent-free mechanochemistry

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Solvent-free mechanochemical conditions have been developed to investigate the significance of ion pairing and the use of weak bases for driving forward nucleophilic substitution reactions. This approach takes advantage of… Click to show full abstract

Solvent-free mechanochemical conditions have been developed to investigate the significance of ion pairing and the use of weak bases for driving forward nucleophilic substitution reactions. This approach takes advantage of the lack of solvent shells to incorporate weaker and safer bases to drive reactions to completion through specific ion pairing pathways. The most efficient reactions contained larger and more polarizable cation and anion pairs.

Keywords: using ion; developing benign; ion; solvent free; syntheses using; benign syntheses

Journal Title: Green Chemistry
Year Published: 2020

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