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In this communication, we disclosed a palladium-catalyzed carbonylative procedure for the synthesis of 1-aroyl-3-aryl-1,5-dihydro-2H-pyrrol-2-ones from propargyl amines and aryl halides. By using TFBen as the CO source, the reaction provides… Click to show full abstract
In this communication, we disclosed a palladium-catalyzed carbonylative procedure for the synthesis of 1-aroyl-3-aryl-1,5-dihydro-2H-pyrrol-2-ones from propargyl amines and aryl halides. By using TFBen as the CO source, the reaction provides a facile and straightforward access to various aryl-substituted 2-oxo-2,5-dihydropyrroles in good yields. The reaction mechanism is proven to be attractive as well.
Keywords:
propargyl amines;
aryl dihydro;
dihydro pyrrol;
palladium catalyzed;
pyrrol ones;
aroyl aryl
Journal Title: Organic chemistry frontiers
Year Published: 2020
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Journal Title: Organic chemistry frontiers
Year Published: 2020
Link to full text (if available)
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recommendations!