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Recent advances in the synthesis and reactivity of quinoxaline

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Quinoxaline has become a subject of extensive research due to its emergence as an important chemical moiety possessing a wide range of physicochemical and biological activities. The last few decades… Click to show full abstract

Quinoxaline has become a subject of extensive research due to its emergence as an important chemical moiety possessing a wide range of physicochemical and biological activities. The last few decades have witnessed several publications utilizing quinoxaline scaffold for the design and development of numerous bioactive molecules, dyes, fluorescent materials, electroluminescent materials as well as organic sensitizers for solar cell applications and polymeric optoelectronic materials. Therefore, to fulfill the need of the scientific community, tremendous effort has been observed in the development of newer synthetic strategies as well as novel methodologies to decorate the quinoxaline scaffold with proper functional groups. Hence, to provide an updated comprehensive account of the diverse synthetic routes to access quinoxaline as well as approach-es for structural diversifications, we have attempted to document the synthetic strategies and their functionalization with possible mechanistic rationalization. This will no doubt be helpful for the readers who are anticipating a comprehensive overview on quinoxaline as well as benefit the researchers for future development.

Keywords: reactivity quinoxaline; development; synthesis reactivity; advances synthesis; recent advances; quinoxaline

Journal Title: Organic chemistry frontiers
Year Published: 2021

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