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Identification of a covalent binder to the oncoprotein gankyrin using a NIR-Based OBOC screening method

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Despite huge advancements in the process of synthesizing small molecules as part of one-bead-one-compound (OBOC) libraries, progress lags in the ability to rank potential hits from a primary library screen. Click to show full abstract

Despite huge advancements in the process of synthesizing small molecules as part of one-bead-one-compound (OBOC) libraries, progress lags in the ability to rank potential hits from a primary library screen.

Keywords: covalent binder; gankyrin using; identification covalent; binder oncoprotein; using nir; oncoprotein gankyrin

Journal Title: RSC Advances
Year Published: 2021

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