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Single gold nanoparticle-driven heme cofactor nanozyme as an unprecedented oxidase mimetic.

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The catalytic diversity of heme enzymes is a perpetuating pursuit for biomimetic chemistry, but heme nanozymes exhibit catalytic activity only reminiscent of peroxidases. Miraculously, the oxidase-like catalytic function of a… Click to show full abstract

The catalytic diversity of heme enzymes is a perpetuating pursuit for biomimetic chemistry, but heme nanozymes exhibit catalytic activity only reminiscent of peroxidases. Miraculously, the oxidase-like catalytic function of a heme cofactor is elicited with the help of gold nanoparticles (AuNPs) by maintaining heme with a low-valence state (ferrous) in a confined configuration.

Keywords: heme; heme cofactor; single gold; gold nanoparticle

Journal Title: Chemical communications
Year Published: 2021

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