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Cyclic ethers are important scaffolds employed in the synthesis of various natural products and pharmaceutical ingredients. A novel free radical-initiated reaction between cyclic ethers and maleimide iodides through C-H activation… Click to show full abstract
Cyclic ethers are important scaffolds employed in the synthesis of various natural products and pharmaceutical ingredients. A novel free radical-initiated reaction between cyclic ethers and maleimide iodides through C-H activation is developed, avoiding the use of transition metallic catalysts. This method provides a simple approach to derive cyclic ethers, which were further applied in various cross coupling reactions.
Keywords:
activation;
maleimide iodides;
cyclic ethers;
ethers maleimide;
direct functionalization
Journal Title: Chemical communications
Year Published: 2021
Link to full text (if available)
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Journal Title: Chemical communications
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!