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Bioactive molecules that enhance or induce osteogenic potential of bone precursor cells have shown vital roles in bone tissue engineering. Herein, we report the design and synthesis of a novel… Click to show full abstract
Bioactive molecules that enhance or induce osteogenic potential of bone precursor cells have shown vital roles in bone tissue engineering. Herein, we report the design and synthesis of a novel diketopiperazine (DT) that induces osteoblastic differentiation of pre-osteoblasts and bone-marrow-derived stem cells in vitro and enhances the osteogenic potential of cryogel matrix. Such functional diketopiperazines can serve as potential scaffolds for bone healing and regeneration.
Keywords:
diketopiperazine;
anionic diketopiperazine;
diketopiperazine induces;
differentiation;
cryogel;
induces osteogenic
Journal Title: Chemical communications
Year Published: 2021
Link to full text (if available)
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Journal Title: Chemical communications
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!