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AIE + ESIPT activity-based NIR Cu2+ sensor with dye participated binding strategy.

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A novel activity-based Cu2+ fluorescent probe featuring multidentate binding sites was synthesized. It functions through chelation with Cu2+, which in turn specifically triggers hydrolysis of the probe to release a… Click to show full abstract

A novel activity-based Cu2+ fluorescent probe featuring multidentate binding sites was synthesized. It functions through chelation with Cu2+, which in turn specifically triggers hydrolysis of the probe to release a near-infrared emission with AIE + ESIPT properties. The probe was found to be capable of ratiometric imaging of Cu2+ in living HeLa cells.

Keywords: esipt activity; aie esipt; activity based; based nir

Journal Title: Chemical communications
Year Published: 2021

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