The isomerization of epoxides to allylic alcohols was developed via proton-accelerated Lewis acid catalysis. The addition of tBuOH as a proton source is the key to the efficient catalytic cycle.… Click to show full abstract
The isomerization of epoxides to allylic alcohols was developed via proton-accelerated Lewis acid catalysis. The addition of tBuOH as a proton source is the key to the efficient catalytic cycle. Trisubstituted epoxides, including enantioenriched derivatives, were selectively converted to secondary-allylic alcohols without loss of enantiopurity.
Keywords:
lewis acid;
isomerization epoxides;
allylic alcohols;
epoxides allylic;
accelerated lewis;
proton accelerated
Journal Title: Chemical communications
Year Published: 2021
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Journal Title: Chemical communications
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!