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Targeting of molecular constituents of thrombi with aptamer functionalized core-shell nanoparticles (CSN) allowed for high resolution clot delineation in T2-weighted magnetic resonance imaging. Meanwhile, the gold-coating demonstrated sufficient contrast capabilities… Click to show full abstract
Targeting of molecular constituents of thrombi with aptamer functionalized core-shell nanoparticles (CSN) allowed for high resolution clot delineation in T2-weighted magnetic resonance imaging. Meanwhile, the gold-coating demonstrated sufficient contrast capabilities in computed tomography (1697 HU μM-1). This targeted CSN formulation could allow for precise imaging of blood clots at low nanomolar concentrations.
Keywords:
gold coated;
functionalized gold;
fibrinogen aptamer;
coated iron;
gold;
aptamer functionalized
Journal Title: Chemical communications
Year Published: 2022
Link to full text (if available)
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Journal Title: Chemical communications
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!