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Membrane transport inspired hydrolysis of non-activated esters at near physiological pH.

A positively charged micelle loaded with substrates was transported selectively to the reaction site (cathode) to promote the proximity and localization of the reactants (ester and hydroxide). The guided vehicular… Click to show full abstract

A positively charged micelle loaded with substrates was transported selectively to the reaction site (cathode) to promote the proximity and localization of the reactants (ester and hydroxide). The guided vehicular delivery coupled with electrolysis allows the hydrolysis of non-activated esters at near physiological pH with significant yields along with recyclability.

Keywords: esters near; hydrolysis non; activated esters; non activated; near physiological

Journal Title: Chemical communications
Year Published: 2021

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