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Probing serum N-glycan patterns for rapid and precise detection of Crohn's disease.

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Serum N-glycan patterns from 50 Crohn's disease (CD) patients and 50 healthy controls were acquired using a carbon matrix, from which eight N-glycans with significant difference were screened out to… Click to show full abstract

Serum N-glycan patterns from 50 Crohn's disease (CD) patients and 50 healthy controls were acquired using a carbon matrix, from which eight N-glycans with significant difference were screened out to reveal remarkale performance for CD diagnosis. This research is expected to help future glycan-based disease detection not limited to CD.

Keywords: glycan patterns; detection; probing serum; disease; serum glycan; crohn disease

Journal Title: Chemical communications
Year Published: 2021

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