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Ultrasensitive pathogen detection with a rolling circle amplification-empowered multiplex electrochemical DNA sensor.

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We report a highly sensitive and selective multiplex assay by empowering an electrochemical DNA sensor with isothermal rolling circle amplification. The assay could simultaneously detect and discriminate three common entero-pathogens… Click to show full abstract

We report a highly sensitive and selective multiplex assay by empowering an electrochemical DNA sensor with isothermal rolling circle amplification. The assay could simultaneously detect and discriminate three common entero-pathogens in a single reaction, with femtomolar sensitivity. It is useful for field- or resource-limited settings.

Keywords: electrochemical dna; dna sensor; rolling circle; circle amplification

Journal Title: Chemical communications
Year Published: 2021

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