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Hydrophobic immiscibility controls self-sorting or co-assembly of peptide amphiphiles.

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Pairs of peptide amphiphiles with immiscible hydrophobic tails were synthesized and their assembly formation was investigated. These pairs formed self-sorting supramolecular fibres using a standard heating-cooling protocol, while one pair… Click to show full abstract

Pairs of peptide amphiphiles with immiscible hydrophobic tails were synthesized and their assembly formation was investigated. These pairs formed self-sorting supramolecular fibres using a standard heating-cooling protocol, while one pair with longer hydrophobic tails formed a co-assembly when an additional heating process was applied.

Keywords: hydrophobic immiscibility; peptide amphiphiles; controls self; sorting assembly; self sorting; immiscibility controls

Journal Title: Chemical communications
Year Published: 2021

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