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Gram-scale production of sugar nucleotides and their derivatives

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Here, we report a practical sugar nucleotide production strategy that combined a high-concentrated multi-enzyme catalyzed reaction and a robust chromatography-free selective precipitation purification process. Twelve sugar nucleotides were synthesized on… Click to show full abstract

Here, we report a practical sugar nucleotide production strategy that combined a high-concentrated multi-enzyme catalyzed reaction and a robust chromatography-free selective precipitation purification process. Twelve sugar nucleotides were synthesized on a gram scale with a purity up to 98%.

Keywords: gram scale; sugar; sugar nucleotides; production sugar; scale production

Journal Title: Green Chemistry
Year Published: 2021

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