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Selective Golgi α-mannosidase II inhibitors: N-alkyl substituted pyrrolidines with a basic functional group

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Enzymatic assays, molecular modeling and NMR studies of novel 1,4-dideoxy-1,4-imino-l-lyxitols provided new information on the GH38 family enzyme inhibitors and their selectivity. Click to show full abstract

Enzymatic assays, molecular modeling and NMR studies of novel 1,4-dideoxy-1,4-imino-l-lyxitols provided new information on the GH38 family enzyme inhibitors and their selectivity.

Keywords: golgi mannosidase; mannosidase inhibitors; alkyl substituted; inhibitors alkyl; substituted pyrrolidines; selective golgi

Journal Title: New Journal of Chemistry
Year Published: 2021

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