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A computational prospective on isoform-selective CB2 inhibitors

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The strategy of enlarging the molecular size, increasing hydrogen bond interactions with the key residues of CB2, and furthering geometric distribution of hydrophobic groups would improve the selectivity towards CB2… Click to show full abstract

The strategy of enlarging the molecular size, increasing hydrogen bond interactions with the key residues of CB2, and furthering geometric distribution of hydrophobic groups would improve the selectivity towards CB2 receptor.

Keywords: prospective isoform; computational prospective; isoform selective; chemistry; cb2 inhibitors; selective cb2

Journal Title: New Journal of Chemistry
Year Published: 2021

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