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Synthesis of enantioenriched α-heteroatom functionalised aldehydes by chiral organocatalysis and their synthetic applications

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Asymmetric organocatalysis is a versatile method for the enantioselective α-functionalisation of aldehydes. The synthetic scope for chiral α-heteroatom substituted aldehydes is examined including their applications in synthesis. Click to show full abstract

Asymmetric organocatalysis is a versatile method for the enantioselective α-functionalisation of aldehydes. The synthetic scope for chiral α-heteroatom substituted aldehydes is examined including their applications in synthesis.

Keywords: organocatalysis; synthesis enantioenriched; enantioenriched heteroatom; heteroatom; heteroatom functionalised; applications synthesis

Journal Title: Organic Chemistry Frontiers
Year Published: 2021

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