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Palladium-catalyzed C8–H arylation and annulation of 1-naphthalene carboxylic acid derivatives with aryl iodides

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Disclosed herein is palladium-catalyzed C8–H arylation and annulation of 1-naphthoic acid derivatives with aryl iodides in a low reactant molar ratio via an electrophilic aromatic substitution (SEAr) process. Click to show full abstract

Disclosed herein is palladium-catalyzed C8–H arylation and annulation of 1-naphthoic acid derivatives with aryl iodides in a low reactant molar ratio via an electrophilic aromatic substitution (SEAr) process.

Keywords: catalyzed arylation; aryl iodides; derivatives aryl; acid derivatives; palladium catalyzed; arylation annulation

Journal Title: Organic chemistry frontiers
Year Published: 2021

Link to full text (if available)


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