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Solvent-free synthesis of propargylamines: an overview

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Propargylamines are a class of compounds with many pharmaceutical and biological properties. A green approach to synthesize such compounds is very relevant. This review aims to describe the solvent-free synthetic… Click to show full abstract

Propargylamines are a class of compounds with many pharmaceutical and biological properties. A green approach to synthesize such compounds is very relevant. This review aims to describe the solvent-free synthetic approaches towards propargylamines via A3 and KA2 coupling reactions covering the literature up to 2021.

Keywords: synthesis propargylamines; solvent free; propargylamines overview; free synthesis

Journal Title: RSC Advances
Year Published: 2021

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