A novel Cu(ii)-catalyzed and acid-promoted highly regioselective oxidation of tautomerizable C(sp3)–H bonds adjacent to 1-Bn-DHIQs was developed. This method was successfully applied in the first total synthesis of canelillinoxine. Click to show full abstract
A novel Cu(ii)-catalyzed and acid-promoted highly regioselective oxidation of tautomerizable C(sp3)–H bonds adjacent to 1-Bn-DHIQs was developed. This method was successfully applied in the first total synthesis of canelillinoxine.
               
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