Photo by nci from unsplash
Uncontrolled haemorrhage is the leading cause in nearly 91% of pre-hospital deaths, which were considered potentially survivable. In particular, severe trauma is susceptible to infection, which further affects the natural… Click to show full abstract
Uncontrolled haemorrhage is the leading cause in nearly 91% of pre-hospital deaths, which were considered potentially survivable. In particular, severe trauma is susceptible to infection, which further affects the natural healing process and can even lead to life-threatening sepsis. Therefore, we established Ag@HMSN nanocomposites based on a yeast cell template that combines hemostasis with antibiosis and further studied the effects of different calcination temperatures on the hemostatic and antibacterial properties. From the experimental results, Ag@HMSNs/500 shows excellent bactericidal effect on a mouse skin infection model and outstanding hemostatic effect on a mouse liver injury model, which could be used as the next-generation hemostatic and antibacterial material.
Journal Title: Biomaterials science
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!