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Quaternary carbon construction through Piancatelli rearrangement: easy access to spirocyclopentenones.

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A new and efficient approach to a series of novel multifunctionalized spirocyclopentenone scaffolds through Piancatelli rearrangement was developed under metal-free conditions. This method has been successfully applied to O-, N-… Click to show full abstract

A new and efficient approach to a series of novel multifunctionalized spirocyclopentenone scaffolds through Piancatelli rearrangement was developed under metal-free conditions. This method has been successfully applied to O-, N- and C-nucleophiles with excellent yields.

Keywords: construction piancatelli; piancatelli rearrangement; carbon construction; quaternary carbon; rearrangement; rearrangement easy

Journal Title: Chemical communications
Year Published: 2022

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