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Towards depeptidized aminoboronic acid derivatives through the use of borylated iminium ions.

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Herein, we use α-boryl iminium intermediates to access progressively depeptidized branched β-aminoboronic acids that are functionalized with biologically relevant heterocycles. We investigate the interaction of these novel compounds with carbohydrates… Click to show full abstract

Herein, we use α-boryl iminium intermediates to access progressively depeptidized branched β-aminoboronic acids that are functionalized with biologically relevant heterocycles. We investigate the interaction of these novel compounds with carbohydrates under physiological conditions and demonstrate their potential as synthetic building blocks.

Keywords: derivatives use; iminium; towards depeptidized; aminoboronic acid; depeptidized aminoboronic; acid derivatives

Journal Title: Chemical communications
Year Published: 2022

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