A novel diastereodivergent tricyclization of isocyanoacetates with o-quinone methides was accomplished for the efficient synthesis of chromeno[2,3-b]chromene derivatives. All three reactive centers of isocyanoacetate reacted sequentially with two o-QMs, affording… Click to show full abstract
A novel diastereodivergent tricyclization of isocyanoacetates with o-quinone methides was accomplished for the efficient synthesis of chromeno[2,3-b]chromene derivatives. All three reactive centers of isocyanoacetate reacted sequentially with two o-QMs, affording the products with four adjacent stereocenters in a diastereoselective manner. The asymmetric version was preliminarily investigated.
Keywords:
synthesis chromeno;
centers isocyanoacetate;
diastereodivergent synthesis;
chromeno chromenes
Journal Title: Chemical communications
Year Published: 2022
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Journal Title: Chemical communications
Year Published: 2022
Link to full text (if available)
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recommendations!